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As Harvard geneticist Dr

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According to the Mayo Clinic, some of these possible interactions include: Substrates for cytochrome P450 2C9, such as Valium (diazepam) and Jantoven (warfarin) Some diabetes medications Evista (raloxifene) Olysio (simeprevir) Rapamune (sirolimus) Other medications, such as those that treat allergies, high cholesterol, anxiety, and cancer, could also interact with milk thistle, according to Mount Sinai

Most patients experience no adverse effects, and when present, theyre typically mild and transient including temporary digestive changes as the gut adjusts, minor nausea (usually resolving within days), or altered bowel patterns during initial therapy

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