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Research topics and evolving patterns In order to systematically categorize the research topics of ongoing studies, and gain insights into the latest unpublished findings, we extracted trials started since 2018 (n = 194) from all included studies and categorized them based on sponsors and interventions (Figure 4)

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These results point to the interconnection between glycolysis (the central metabolic pathway in erythrocytes), energy metabolism, and cation channel-driven eryptosis