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Shaking creates bubbles and mechanical stress that can break the fragile bonds in a peptide

Article reviewed by Dr Chua Hshan Cher, Head of Family Medicine at Phoenix Medical Group.

Additional regional factors such as high baseline HBV endemicity (5-18%), dietary aflatoxin exposure, and lower NAFLD prevalence further limit direct extrapolation (105)

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These pathophysiological mechanisms have the potential to form a vicious circle that further aggravates the development of HF ( Figure 4 )