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Standard testosterone replacement therapy suppresses the hypothalamic-pituitary-gonadal (HPG) axis, which reduces the pituitarys signaling to the testes

Patients who prefer less frequent dosing or who have trouble remembering to take daily medication may prefer injections

Psychosom Med 2019;81(7): 570583

the exact volume depends on the concentration a given research protocol calls for

Your nausea and vomiting are very strong

For some individuals, the dose may need to be adjusted based on how well they respond to the medication and how comfortable they feel with the side effects