gut microbes glp-1 activity link and GLP-2 Orchestrate Intestine Integrity, Microbiota, and Immune System Crosstalk Implement enhanced artificial “enteroendocrine L

H&E staining results further confirmed that the aortic wall thickness of mice treated with FOXO4-DRI was significantly thinner, and ultrasound examination results showed that the PWV of the aorta was slowed down after FOXO4-DRI treatment, indicating better vascular elasticity and significantly improved vascular function compared to the control group (Figures 2D,E)

Druker, B

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This defect was linked to impaired brown adipose tissue thermogenesis, 6 as reflected by reduced mitochondrial respiration and decreased circulating long-chain acylcarnitines (Fig