De vorm van L-carnitine L-carnitine komt in meerdere vormen, waarbij iedere vorm weer voor andere doeleinden van belang is
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Keywords: Autism, Carnitine, Neurodevelopmental, Metabolism, Pathophysiological bases Core tip: Autism spectrum disorder is characterized by impaired communication, altered social skills, stereotypical behaviors and limited interests
TMAO has been shown to trigger inflammation and senescence in endothelial cells, causing barrier disruption and subsequent interaction with neurons
Autophagy defects lead to the accumulation of depolarized mitochondria and proteins and induce the release of inflammatory body activator (ROS or mitochondrial DNA) [92, 93]
whereas at 13 weeks, enhanced brain cell damage was suggested by reduced fission and autophagosome markers, as well as increased apoptosis and DNA fragmentation markers, which were partially reversed by maternal L-Carnitine supplementation