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Every body is different, but these groups may be more sensitive to cycle changes: People with PCOS Anyone with a history of hypothalamic amenorrhea or disordered eating Those in perimenopause or postpartum (due to hormone levels that are already fluctuating) People with rapid or large weight loss in a short time This doesnt necessarily mean Zepbound isnt right for you it just means your cycle may need a little extra attention along the way

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