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Its triple agonism allows simultaneous study of combined GLP-1 + GIP + glucagon effects, experimental dissections impossible with mono-agonists or dual agonists

Of 541 participants assessed, 56.7% had 1 manual dose change during the trial

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This was mediated by the recognition of cadaverine by Trace amino acid receptors (TAAR1, TAAR8, and TAAR9) [241]