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The Pan African Medical Journal

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149,150,151 These receptors each have independent yet complementary roles in the treatment of diabetes and obesity

The initiative also mentions Advanced Research Projects Agency for Health (ARPA-H) computational programs whose grantees are working on new ways of predicting drug safety and efficacy, and methods to integrate electronic health records and information from the national clinical trials database

Because they are naturally occurring compounds or close analogs to substances already in the body, they typically have favorable safety profiles