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Clinical trials show that many people with prediabetes who use semaglutide return to normal blood sugar levels, especially when combined with diet and exercise

GIP also helps with insulin release, but researchers believe that when it works in concert with GLP-1, the combination has a powerful, complementary effect on the body's overall energy balance and how it stores fat

Safety and tolerability of semaglutide across the SUSTAIN and PIONEER phase IIIa clinical trial programmes

The rebrand of the Ozempic pill may reflect a broader shift in diabetes care toward GLP-1based therapies, with the FDA approving Foundayo, an oral GLP-1 receptor agonist from Eli Lily, in April 2026

They mostly used 5- and 4-mm needles (30.6% and 28.5%, respectively), with 20.0% using the 6-mm needles and 20.6% using 8-mm ones

GLP-1 medications should be used under the care of a licensed medical provider