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Efficacy of DSIP to normalise sleep in middle-aged and elderly chronic insomniacs

Merritt K, Egerton A, Kempton MJ, Taylor MJ, McGuire PK

GHK-Cu provides a double-layered defense: Anti-Inflammatory: It reduces pro-inflammatory cytokines that trigger follicle "shutdown." Antioxidant: It neutralizes free radicals, protecting the follicle's DNA from environmental damage and aging

EDC/NHS chemistry was used to graft functional groups (alanine and GSH), couple therapeutic molecules (ibuprofen and dopamine) on PLG backbone and label the co-polypeptides with R6G (Fig