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GLP-1s often lead to 3050 pounds of weight loss, while surgery can result in far greater total body weight reduction, particularly in those with a BMI over 40 or severe obesity-related health issues

Tiffany Lowe Clayton, a bariatric physician and obesity specialist at WakeMed, said GLP-1 medications work on receptors in both the brain and the digestive system, which can affect a person's perception of thirst

it also happens to deliver weight loss approaching what Wegovy achieves at 2.4 mg

Coadministered Cagrilintide and semaglutide in adults with overweight or obesity

This treatment mimics the GLP-1 hormone, targeting brain regions that control appetite and food intake, effectively reducing hunger and enhancing feelings of fullness

2 , there may also be important timing-related considerations to make when empirically investigating the influence of GLP-1 agonists on sexual desire