L., Bengtsson, B.-., Rmer, J., Ahnfelt-Rnne, I., Ohlsson, C., & Jansson, J.-O
In addition to iron-catalyzed free radical chain reactions, lipoxygenase (LOXs) can directly oxidize PUFAs and lipid-containing PUFAs in cell membranes, which are considered to have an essential role in ferroptosis [75, 80]
5.2 Mitochondrial stability and antioxidant effects Although the effects of omega-3 PUFAs on ROS production within mitochondria have yielded mixed results, omega-3 PUFAs are known to influence mitochondrial function in several ways, including impacts on membrane potential, respiration rates, the activity of mitochondrial complexes, and ROS production
Further, overproduction of free radicals have also been shown to occur due to spontaneous breakdown (autoxidation) and/or excessive metabolism by monoamine oxidase of adrenaline, noradrenaline and dopamine, which can further overwhelm the brains antioxidant systems (Cohen, 1984
This overlap is evident in the shared molecular mechanisms between kindled seizures and LTP, both induced by similar neural activities
Eseberri I, Lasa A, Churruca I, Portillo MP (2013) Resveratrol metabolites modify adipokine expression and secretion in 3T3-L1 pre-adipocytes and mature adipocytes
