Categorical variables were summarized as frequencies and percentages and compared using the chi-square test or Fishers exact test where appropriate
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10.1161/CIRCULATIONAHA.113.007124 Circulation
Targets and calculations are briefly summarized: Dependency Equation (1), Capacity Equation (2), and Flexibility (i.e
However, increasing structural and compositional complexity introduces challenges related to long-term safety evaluation, regulatory approval, and reproducible manufacturing, highlighting the need for rigorous validation frameworks [183]
